| | Day | Time | | Opponent | Score | | Record | |
| February |
| | 12 | 1:00 PM | vs. | Texas Southern University | W-7-6 | | 1-0 | Details |
| | | Game 2 | vs. | Texas Southern University | L-3-4 | | 1-1 | Details |
| | 15 | 5:00 PM | vs. | Huston-Tillotson College | W-10-1 | | 2-1 | Details |
| | UHV's Baylea Wagener lost no-hit bid in fifth |
| | | Game 2 | vs. | Huston-Tillotson College | W-13-1 | | 3-1 | Details |
| | Game called in fifth inning |
| | 18 | 11:00 AM | vs. | Oklahoma City University | L-0-5 | | 3-2 | Details |
| | St. Gregory University Invitational - in Farmers Branch |
| | | 4:00 PM | vs. | Belhaven University | L-8-11 (8 Innings) | | 3-3 | Details |
| | St. Gregory's University Invitational in Farmers Branch |
| | 19 | 10:00 AM | vs. | Saint Gregory's University | W-3-2 | | 4-3 | Details |
| | St. Gregory University Invitational - in Farmers Branch |
| | | 12:30 PM | vs. | Friends University | W-7-2 | | 5-3 | Details |
| | St. Gregory's University Invitational in Farmers Branch |
| | 26 | 2:00 PM | vs. | Our Lady of the Lake University | L-2-3 | | 5-4 | Details |
| | | Game 2 | vs. | Our Lady of the Lake University | W-7-2 | | 6-4 | Details |
| March |
| | 5 | 1:00 PM | vs. | Texas College | W-15-0 | | 7-4 | Details |
| | Dawn Villegas pitched a one-hitter |
| | | Game 2 | vs. | Texas College | W-20-0 | | 8-4 | Details |
| | Emily Bergstrom pitched a one-hitter |
| | 8 | 1:00 PM | @ | Texas College | W-13-0 | | 9-4 | Details |
| | | Game 2 | @ | Texas College | W-10-2 | | 10-4 | Details |
| | 11 | 12:00 PM | vs. | Southern Nazarene University | L-5-6 (8 Innings) | | 10-5 | Details |
| | Orange Beach Gulf Coast Invitational |
| | | 4:00 PM | vs. | Lee University | W-1-0 | | 11-5 | Details |
| | Orange Beach Gulf Coast Invitational |
| | 12 | 1:00 PM | vs. | Thomas University | L-3-4 | | 11-6 | Details |
| | Gulf Coast Invitational |
| | | 5:00 PM | vs. | Spring Hill College | W-6-1 | | 12-6 | Details |
| | Orange Beach Gulf Coast Invitational |
| | | 7:00 PM | vs. | Saint Gregory's University | L-7-8 | | 12-7 | Details |
| | Orange Beach Classic - Mar. 11-13 |
| | 13 | 9:00 AM | vs. | William Woods University | W-7-1 | | 13-7 | Details |
| | Orange Beach Gulf Coast Invitational |
| | | 1:00 PM | vs. | Central Methodist College | W-9-4 | | 14-7 | Details |
| | Orange Beach Invitational |
| | | 5:00 PM | vs. | Auburn University Montgomery | W-10-0 | | 15-7 | Details |
| | Orange Beach Invitational Consolation Final |
| | 16 | 12:00 PM | @ | Texas A&M-Corpus Christi | L-0-3 | | 15-8 | Details |
| | | Game 2 | @ | Texas A&M-Corpus Christi | L-2-10 | | 15-9 | Details |
| | 22 | 2:00 PM | @ | Prairie View A&M University | W-5-1 | | 16-9 | Details |
| | | Game 2 | @ | Prairie View A&M University | W-7-2 | | 17-9 | Details |
| * | 25 | 1:00 PM | vs. | Central Baptist College | L-2-10 | | 17-10 0-1 | Details |
| * | | Game 2 | vs. | Central Baptist College | W-7-5 | | 18-10 1-1 | Details |
| | Loss was the first of the season for CBC |
| * | 26 | 1:00 PM | vs. | LSU - Alexandria | W-4-1 | | 19-10 2-1 | Details |
| | Houston-Victoria Ranked #16 |
| * | | Game 2 | vs. | LSU - Alexandria | W-11-0 | | 20-10 3-1 | Details |
| | Bergstrom throws 3-hit shutout/ Houston-Victoria Ranked #16 |
| | 29 | 2:00 PM | @ | Texas Southern University | W-8-6 | | 21-10 | Details |
| | | Game 2 | @ | Texas Southern University | L-3-4 | | 21-11 | Details |
| April |
| | 2 | 1:00 PM | vs. | Houston Baptist University | L-2-9 | | 21-12 | Details |
| | | Game 2 | vs. | Houston Baptist University | W-5-4 | | 22-12 | Details |
| | 5 | 4:00 PM | @ | Concordia University-Texas | W-6-1 | | 23-12 | Details |
| | | Game 2 | @ | Concordia University-Texas | W-10-3 (8 Innings) | | 24-12 | Details |
| * | 9 | 1:00 PM | @ | LSU - Alexandria | W-15-2 | | 25-12 4-1 | Details |
| * | | Game 2 | @ | LSU - Alexandria | W-11-5 | | 26-12 5-1 | Details |
| | 12 | 3:00 PM | @ | Huston-Tillotson College | W-3-0 | | 27-12 | Details |
| | UHV's Emily Bergstrom pitched a perfect game |
| | | Game 2 | @ | Huston-Tillotson College | L-3-4 (8 Innings) | | 27-13 | Details |
| | 16 | 1:00 PM | vs. | Prairie View A&M University | W-3-0 | | 28-13 | Details |
| | Emily Bergstrom tosses 3-hit shutout |
| | | Game 2 | vs. | Prairie View A&M University | W-5-0 | | 29-13 | Details |
| | Dawn Villegas tosses 3-hitter for UHV |
| | 19 | 1:00 PM | @ | Our Lady of the Lake University | W-19-6 | | 30-13 | Details |
| | Jaguars banged out a single-game high 26 hits |
| | | Game 2 | @ | Our Lady of the Lake University | W-3-1 | | 31-13 | Details |
| | 22 | 1:00 PM | vs. | Texas Southern University | L-3-4 | | 31-14 | Details |
| | UHV Invitational |
| | | 6:00 PM | vs. | Texas Wesleyan University | W-8-0 (5 Innings) | | 32-14 | Details |
| | UHV Invitational |
| | 23 | 11:30 AM | vs. | Texas Wesleyan University | W-4-2 (9 Innings) | | 33-14 | Details |
| | UHV Invitational |
| | | 1:00 PM | vs. | Texas Southern University | W-3-2 | | 34-14 | Details |
| | UHV Invitational |
| | 30 | 1:00 PM | @ | Houston Baptist University | L-1-2 | | 34-15 | Details |
| | | Game 2 | @ | Houston Baptist University | L-0-1 | | 34-16 | Details |
| May |
| | 5 | 1:00 PM | vs. | Patten University | W-8-1 | | 35-16 | Details |
| | Opening round of A.I.I. Conference Tournament |
| | | 6:00 PM | vs. | Central Baptist College | L-4-6 | | 35-17 | Details |
| | A.I.I. Conference Tournament |
| * | 6 | 12:00 PM | vs. | University of British Columbia | W-11-4 | | 36-17 6-1 | Details |
| | A.I.I. Conference Tournament |
| * | | 6:00 PM | @ | California State University-San Marcos | W-2-1 (13 Innings) | | 37-17 7-1 | Details |
| | A.I.I. Conference Tournament |
| * | 7 | 12:00 PM | vs. | Central Baptist College | L-1-2 | | 37-18 7-2 | Details |
| | A.I.I. Conference Softball Tournament |